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KMID : 0602819990050020222
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Korean Journal of Bronchoesophagology
1999 Volume.5 No. 2 p.222 ~ p.230
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A Case of Varicella-Zoster virus infection with multiple cranial nerve involvement
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Abstract
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Varicella-zoster virus(VZV) becomes latent in the sensory ganglia after primary
infection and emerges from latency to cause zoster in adults. After primary infection,
VZV remains latent in the dorsal spinal ganglia. The mechanisms responsible for its
reactivation and the clinical entity of herpes zoster are poorly understood. Reactivation of
VZV is commonly known to manifest as Ramsay Hunt syndrome which is one of the
VZV-associated neurologic diseases with facial paralysis, ear pain, and a characteristic
herpetic auricular rash. It is now known that lesions of this syndrome can affect all
cranial nerves. Central, cervical and peripheral effects of this syndrome is
polyneuropathic in nature. VZV usually involves the 5th and 7th cranial nerves and less
commonly the lower cranial nerves such as 9th and 10th. We report a treated case of
healthy 40 years old male with VZV infection of the 5th, 9th and 10th cranial nerves.
The patient typically showed herpetic vesicles in the auricle and temporal bone area
without facial paralysis.
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KEYWORD
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